Influences in CT scan lung nodule volumetry.

Lung nodule measurements made with CT imaging are used in clinical practice to assess size changes estimated from serial scans obtained over time to predict the likelihood of malignancy and to monitor the tumor response to treatment. 2 Size measurements need to be accurate and consistent to enable the assessment of nodule changes in a short time interval. Th e precision and accuracy of volume measurements depend on several factors, including the image-acquisition and reconstruction parameters, the nodule characteristics, and the performance of algorithms for nodule segmentation and volume estimation. 2 4